Splenectomy in Immune Thrombocytopenia: When, Why and How?

Bogdan Socea1,2,5, Camelia Diaconu1,2,6, Ovidiu Gabriel Bratu1,3,7, Anca Pantea Stoian1,2,8, Vlad Denis Constantin1,4,5

1 “Carol Davila” University of Medicine and Pharmacy, Bucharest România, 2 MD, PhD, Lecturer, 3 MD, PhD, Assistant Professor, 4 MD PhD, Professor, 5 Surgery, 6 Internal Medicine, 7 Urology, 8 Diabetes, Nutrition and metabolic diseases

Primit: 15.12.2018 • Acceptat pentru publicare: 21.12.201


Immune thrombocytopenia (ITP) is an acquired haemorrhagic disease characterized by the presence of isolated thrombocytopenia (platelet count in peripheral blood <100,000 / mm3). Corticotherapy is recommended as the first-line ITP treatment, but splenectomy remains, although it has the greatest chances to cure the disease, a second-line option in ITP therapeutic management.

Classic surgical spleen removal can be associated with several complications: infection, cardiovascular events and cancer. The modern surgical approach consists of laparoscopic splenectomy, being preferred to the classical method due to reduced complications, faster recovery and is both a palliative and a curative method.

Palliative irradiation therapy of spleen is another option to annihilate this organ in ITP.

Keywords: splenectomy, immune thrombocytopenia, laparoscopic surgery, palliative irradiation

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